EchoTip AcuCore Post-Market Clinical Study

Inclusion Criteria: * Patient has been referred for an endoscopic ultrasound (EUS) fine needle biopsy procedure * The EchoTip AcuCore device is the first EUS biopsy needle used in the procedure. Exclusion Criteria: * Patient's age is less than 18 years * Patient is unable or unwilling to sign and date the informed consent. If IRB approves a waiver of consent, this exclusion criterion is not applicable. * Patient is simultaneously participating in another pre-market investigational drug or pre-market investigational device study involving an EUS fine needle biopsy procedure and for which the patient has not completed the follow-up phase for the primary endpoint at least 30 days prior to enrollment in this study. * Inaccessible or unsuitable lesion (lesion not visualized or a large vessel, duct or primary mass interposition)