This study will help researchers learn more about how babies respond to bottle nipples with larger or smaller holes. Researchers guess that infants of mothers with obesity who did not lose weight prior to pregnancy will have the greatest Suck Effect on the challenging compared with the typical nipple.
The researchers will recruit babies from the original cohort in the PLAN study (NCT03244722), regardless of which arms they participated in. However, the researchers will test the study arms from the original PLAN study for effects on the study's dependent variables. Their between-subjects arms included Pre-pregnancy obesity with intensive weight loss intervention, pre-pregnancy obesity with standard of care intervention, and pre-pregnancy healthy weight with no intervention. So, although the researchers are not assigning babies to any arms, their original assignment will still be assessed the study analysis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
30
Infants are fed their typical milk/formula by their caregiver when hungry, one feeding with their typical nipple.
Infants are fed with a smaller sized nipple (i.e. with a smaller aperture, slowing the rate of milk delivery).
The University of Michigan
Ann Arbor, Michigan, United States
Suck effect
Sucking will be measured with the NFANT® Feeding Solution
Time frame: Up to 6 weeks
Sucking pressure
Sucking will be measured with the NFANT® Feeding Solution
Time frame: Up to 6 weeks
Sucking frequency
Sucking will be measured with the NFANT® Feeding Solution
Time frame: Up to 6 weeks
Milk/Formula intake
Time frame: Up to 6 weeks
Milk/Formula consumption rate
Time frame: Up to 6 weeks
Number of Feedings Over 24 Hours
Time frame: Up to 6 weeks
Total Hours of Sleep per 24 Hours within 24 hours of intervention
Time frame: Up to 6 weeks
Total Night Wake-ups within 24 hours of intervention
Time frame: Up to 6 weeks
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