Bispecific antibody (BsAb) treatments, teclistamab and elranatamab, are newly available for patients with multiple myeloma who are refractory to all current drugs. The results are very encouraging but complicated adverse events, particularly infectious. This study analyzes survival data in patients treated with BsAb, as well as safety data, in particular the proportions and locations of infectious events. The results are compared to a control cohort. This study is multicentric on all the university hospitals of Paris (AP-HP).
Bispecific antibody (BsAb) treatments, teclistamab and elranatamab, are newly available for patients with multiple myeloma who are refractory to all current drugs. The results are very encouraging but complicated adverse events, particularly infectious. This study analyzes survival data in patients treated with BsAb, as well as safety data, in particular the proportions and locations of infectious events. The results are compared to a control cohort. This study is multicentric on all the university hospitals of Paris (AP-HP).
Study Type
OBSERVATIONAL
Enrollment
600
Treated by bispecific antibodies, teclistamab or elranatamab in usual care
Not treated by bispecific antibodies in usual care
Assistance Publique - Hôpitaux de Paris (AP-HP)
Paris, IDF, France
Infection rate
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Time frame: Up to 18 months
Global survival
Explore the global survival
Time frame: Up to 18 months
Progression-free survivals
Explore the progression-free survivals
Time frame: Up to 18 months
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