Dialysis patients have a higher incidence of cardiovascular events and require more effective measures to delay the progression of heart failure. Many studies have shown that dapagliflozin has cardioprotective effect, but most studies focus on non-dialysis patients with eGFR more than 20ml/min/1.73m2. However, the data on patients with eGFR less than 20ml/min/1.73m2 or dialysis patients, especially peritoneal dialysis patients, is less. Exploring the efficacy and safety of Dapagliflozin in improving heart failure in dialysis patients is of great clinical significance.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
40
oral Dapagliflozin tablets 10mg/day for 6 months
The People's Hospital of Gaozhou
Maoming, Guangdong, China
RECRUITINGN-terminal B-type natriuretic peptide precursor (NT-proBNP)
Changes in NT-proBNP levels before and after treatment
Time frame: Baseline, 3 months, 6 months
Left ventricular ejection fraction (LVEF)
Changes in LVEF levels before and after treatment
Time frame: Baseline, 3 months, 6 months
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