This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair. Although Pregabalin is known to be effective in controlling pain after shoulder arthroscopy, research on its efficacy in pain management for patients with central sensitization is scarce. Utilizing a list that identifies central sensitization, this study will explore whether Pregabalin can reduce postoperative pain in these patients and potentially improve joint mobility, emotional, and physical functioning. A prospective randomized study is planned, with inclusion criteria set for patients aged between 19 and 70 who have undergone arthroscopic rotator cuff repair. The study will compare clinical outcomes up to one year postoperatively between two groups of 38 patients each. The case group will receive standard postoperative medications (NSAIDs) plus Pregabalin oral intake from the day before surgery to six weeks postoperatively, while the control group will receive only the standard postoperative medications without Pregabalin.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
76
Pregabalin oral intake from the day before surgery to six weeks postoperatively
The Visual Analogue Scale (VAS) pain score
Pain score evaluation from 0 to 10, 10 meaning the maximum pain
Time frame: Preoperative, postoperative 2, 6 weeks, 2, 4, 6 and 12 months
Constant shoulder score
Shoulder functional score from 0 to 100, 100 meaning excellent shoulder function
Time frame: Preoperative, postoperative 6 months and 12 months
American shouler and elbow surgeons (ASES) score
Shoulder functional score from 0 to 100, 100 meaning excellent shoulder function
Time frame: Preoperative, postoperative 6 months and 12 months
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