The standard treatment of bleeding gastric varices is obliteration with placement of coil and glue. Our study will evaluate the efficacy of EUS guided coil as primary prophylaxis for high-risk gastric varices. All procedures will be performed with patient under deep sedation or general anaesthesia under the supervision of an anaesthesiologist.
In this study Principal investigator recruiting patients with high-risk gastric varices for primary prophylaxis. Gastric varices are dilated submucosal veins in the lining of the stomach, found in patients with portal hypertension or elevated pressure in the portal venous system. The standard treatment of bleeding gastric varices is obliteration with placement of coil and glue. Our study will evaluate the efficacy of EUS guided coil as primary prophylaxis for high-risk gastric varices. All procedures will be performed with patient under deep sedation or general anaesthesia under the supervision of an anaesthesiologist. After the procedure patients will be discharged to home unless there is any indication for admission, such as significant abdominal pain, bleeding or chest pain. For enrolment into the study, patient has to sign an informed consent form which is provided at the end. First, we will do baseline evaluation of the patient which includes detailed clinical examination, routine laboratory tests, Upper GI Endoscopy, triphasic CT abdomen. The duration of study is 6 months. Only the routine tests necessary for the management of disease will be charged.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
50
The standard treatment of bleeding gastric varices is obliteration with placement of coil and glue
Asian institute of Gastroenterology
Hyderabad, Telangana, India
RECRUITINGThe outcome will measure number of patient had achieved complete obliteration of varices
Repeat Endoscopic ultrasound findings of residual flow
Time frame: 6 months for observation
Number of patient needed re intervention
Repeat coil application on follow-up
Time frame: 6 months for observation
Number of patient needed had bleeding following intervention like immediate (with in 5 days) or later (5-90 days)
These are the definite data which will be statistically analyzed
Time frame: 90 days
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