Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders.
Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders. Beside genetic factors, several environmental factors such as injuries, infections, stress, drugs, and immune defect take part in autoimmune pathogenesis of the disease. In addition, it has been reported that some hormones may also have a role in the pathogenesis of psoriasis, due to their effects on keratinocytes proliferation. Studies revealed that sex hormones manifest a variety of biological and immunological effects in the skin which modulate the natural course of psoriasis. Approximately 20-30% of patients with psoriasis may also have psoriatic arthritis, which often causes significant musculoskeletal pain that significantly impairs quality of life (QoL). Although sexual dysfunction is a common complaint, affecting 30 to 70% of psoriasis patients, few studies have analyzed the impact of psoriasis and psoriatic arthritis on quality of sexual life.
Study Type
OBSERVATIONAL
Enrollment
180
to assess the frequency rates of sexual problems and associated factors in a cohort of married females with Psoriatic arthritis, and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients.
Qena Hospital
Qina, Egypt
Evaluation of female sexual function
To identify and understand the mechanisms of sexual problems in Psoriatic arthritis Patients in Qena university hospital.
Time frame: 6 months
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