Effect of Platelet Rich Plasma on Outcome of Narrow Band UVB in Treatment of Vitiligo; Clinical and Histopathological Study

N/AActive Not RecruitingNCT06370650

Sohag University30 enrolled

Overview

For each patient, one side of body will be treated with NB-UVB alone while the other side will be treated with NB-UVB therapy in addition to intradermal injection of PRP every 2 weeks. Patients will be photographed at the first visit, in the middle and at the end of therapy. Each patient will sign a written consent form to be included in the study and to be photographed.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Management of Stable Vitiligo

Interventions

platelet rich plasma, narrow band UVBPROCEDURE

Role of PRP in treating stable vitiligo

Eligibility

Sex: ALLMin age: 15 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients with stable non segmental vitiligo. (Absence of koebnerization, absence of new lesion and absence of widening of the existing lesions). Patients have more than 15 years. \- Exclusion Criteria: Patients have active vitiligo (appearance of new lesion, history of koebnerization). Pregnant and lactating women. History of keloid formation. Anemia (hemoglobin level \<10gm/dl), thrombocytopenia (platelet count \<100,000 /µL), coagulopathies or patients on anticoagulant therapy and patients with iron deficiency. Patients taking drugs that prolong bleeding time such as Aspirin and vitamin E Patients taking treatment of vitiligo in last 2 months

Locations (1)

Faculty of Medicine, Sohag University

Sohag, Egypt

Outcomes

Primary Outcomes

Improvement of vitiligo

increase repigmentation score

Time frame: within 6 months

Data from ClinicalTrials.gov

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