Creatine and GAA for Brain Oxygenation

University of Novi Sad, Faculty of Sport and Physical Education19 enrolled

Overview

The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of cognitive tests.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Oxygen Deficiency

Interventions

SupplementDIETARY_SUPPLEMENT

Dietary supplement containing creatine and guanidinoacetic acid

PlaceboDIETARY_SUPPLEMENT

Inert substance

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-30 years * Absence of metabolic disorders or other health complications * Provision of signed informed consent Exclusion Criteria: * History of dietary supplement use within the preceding 4 weeks * Lack of consent to randomization * Concurrent participation in other studies

Locations (1)

Applied Bioenergetics Lab at Faculty of Sport and PE

Novi Sad, Vojvodina, Serbia

Outcomes

Primary Outcomes

Brain oxygen saturation

Percentage of oxygen saturation in prefrontal brain

Time frame: Change from baseline brain oxygen saturation at 2 weeks

Secondary Outcomes

Hemoglobin index

Concentration of hemoglobin index in prefrontal brain

Time frame: Change from baseline hemoglobin index at 2 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.