A Phase 1 Study of TE-8214 Solution in Healthy Volunteers

Inclusion Criteria: 1. Adult, between 18 and 64 years old (inclusive, at the time of informed consent). 2. In good general health, as determined by past medical history, physical examination, vital signs, ECG, and laboratory tests at Screening and/or before the administration of IP at the discretion of the PI or designee. 3. Sign informed consent forms which include an explanation of the nature of the study, and the expected compliance with the requirements and restrictions of the study. Exclusion Criteria: 1. Any abnormal laboratory values at Screening that are considered clinically significant by the PI or designee, or evidence of clinically significant abnormal findings at the physical examination at Screening, or significant illness within 2 weeks prior to dosing. 2. Have known allergies to octreotide, somatostatin analogs, or related compounds. 3. Have abnormal ECG findings at Screening that are considered by the PI or designee to be clinically significant, including, but not limited to: PR interval \> 220 ms, QTcF \> 450 ms (males) or \> 470 ms (females), and/or arrythmias. 4. History of clinically significant allergy (including anaphylaxis), history or clinical evidence of pancreatic injury or pancreatitis. 5. History of gallstones, prior cholecystectomy is not exclusionary. 6. History of B12 deficiency. 7. History of hypothyroidism, or TSH \> 4 mIU/L at Screening. 8. Any individual with a known history of diabetes mellitus, or HbA1c ≥ 6.5% at Screening. Individuals with previous gestational diabetes are eligible to participate, provided they do not currently have diabetes. 9. Women of childbearing potential (WOCBP) must be non-pregnant and must use an acceptable, highly effective double contraception from Screening until study completion. 10. Males must use an acceptable, highly effective double contraception from Screening until study completion and must not donate sperm until at least 90 days after the last dose of study drug. 11. Anything that the PI considers that would jeopardize the safety of the participant, prevent complete participation in the study, or compromise interpretation of study data. 12. Any skin condition and/or tattoo that may interfere with the evaluation of safety at the injection site.