Longitudinal Evaluation of Antibody Kinetics of Vaccinated Patients With Non-mandatory Vaccine Following Administration of a Non-public Marketed Vaccine in the General Population, Real-life Study

N/ANot Yet RecruitingNCT06373510

CerbaXpert10,000 enrolled

Overview

The study would make it possible to document more explicitly the evolution of antibody titers at following a non-public vaccination over a large post-vaccination period in the French population . Analysis of real-life data would enhance knowledge of vaccine response kinetics It would be useful to identify possible early declines requiring doses Similarly, by analyzing antibody kinetics by age, sex, and vaccination status, the would be possible to determine whether there are differences in the immune response between these different sub-groups. In addition, it would provide additional information to assess the real impact of these non-public vaccines in public health and guide vaccine policies.

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

10,000

Conditions

Vaccination Reaction

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Subject over 18 years of age * Subject presenting to the investigation centre as part of its usual management (prevention, screening, tracking) * Subject who has been vaccinated and/or wishes to be vaccinated * Subject able to understand the purpose of research that has given free and informed express consent * Member or beneficiary of a social security scheme Exclusion Criteria: * Protected subject: major under guardianship, curatorship or other legal protection, deprived of liberty by decision judicial or administrative

Outcomes

Primary Outcomes

Quantification of specific serum antibodies (IgM, IgG) at different times before and/or after vaccination by a reference technique such as ELISA.

Time frame: 3 years