Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis

Inclusion Criteria: * Written informed consent signed by the participant him/herself * Males and females of age 18 or older * Infected with S. stercoralis (positive by at least two Baermann assays on two different days and infection intensities of at least 0.75 LPG in the two stool samples. * Agree to comply with the study procedures, including to be examined by a study physician at the beginning of the study and to provide three stool samples during the screening period (within a maximum of 10 days) and approximately three weeks after treatment (follow-up). * Female participants of childbearing potential to ensure adequate contraception during the study period. Exclusion Criteria: * No written informed consent by individual. * Presence of acute or uncontrolled systemic illnesses (e.g. severe anemia, clinical malaria) as assessed by a medical doctor, upon initial clinical assessment. * Recent history of acute or severe chronic disease, as assessed by a medical doctor or reported by the participant: Type 1 and/or 2 diabetes; Psychiatric disorders; Chronic heart, liver, or renal disease * Prior treatment with anthelmintics (eg, diethylcarbamazine \[DEC\], suramin, ivermectin, mebendazole or albendazole) within 4 weeks before planned study drug administration. * Actively participating in other clinical trials during the study. * Positive pregnancy test or breastfeeding women and planning to become pregnant within three months of study drug administration. * Received strong CYP3A4 inducers or inhibitors as well as concomitant treatments that are relevant substrate for CYP3A4 such as clarithromycin, erythromycin and rifampicin within 4 weeks before planned study drug administration. * Received strong P-gp inhibitors as well as concomitant treatments that are relevant substrates for P-gp such as clotrimazole and ritonavir. * Known allergy to study drugs or any of the ingredients