The study aims to predict the failure of High-flow Nasal Cannula oxygenation therapy by ultrasound evaluation of diaphragm and intercostal muscle contraction during the first 24 hours.
Study Type
OBSERVATIONAL
Enrollment
200
Shanghai Zhongshan Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGUltrasound evaluation of diaphragm
Thickness of the diaphragmatic muscle and the diaphragm thickening fraction (DTF) by ultrasound evaluation
Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
Ultrasound evaluation of intercostal muscle movement index
the parasternal intercostal muscles thickening fraction by ultrasound evaluation
Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
The patient's condition deteriorated and required noninvasive or intubated invasive mechanical ventilation.
Failing or not failing HFNC, the rate of needing noninvasive or intubated invasive mechanical ventilation.
Time frame: up to 30 days after High-flow Nasal Cannula (HFNC)oxygenation therapy.
ICU stay
patients enrolled will be followed for length of ICU stay
Time frame: up to one month after High-flow Nasal Cannula (HFNC)oxygenation therapy.
Hospital stay
patients enrolled will be followed for length of Hospital stay
Time frame: up to one month after High-flow Nasal Cannula (HFNC)oxygenation therapy.
all cause mortality
all cause mortality
Time frame: up to one month after High-flow Nasal Cannula (HFNC)oxygenation therapy.
Oxygen saturation
Oxygen saturation
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Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
respiratory rate
respiratory rate
Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
oxygen concentration
oxygen concentration
Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
flow velocity of HFNC
flow velocity of HFNC
Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
VT
VT
Time frame: Six times a day by the 0,2,6,12,18,24 hours following initiation of High-flow Nasal Cannula (HFNC)oxygenation treatment.
duration on HFNC
patients enrolled for the duration of HFNC
Time frame: up to one month