Effects of Topical Sesame Oil in the Prevention of Peripheral Venous Catheter Phlebitis: Clinical Trial.

Hospital Universitario Marqués de Valdecilla300 enrolled

Overview

Cancer is a disease that, despite having a higher cure rate, is currently on the rise, with an increase in the number of diagnoses. For the treatment of these patients a venous access is required, which in the first treatments is of peripheral insertion. These peripheral venous catheter in combination with the highly aggressive treatments for the veins are the cause of the appearance of chemical phlebitis. Phlebitis is an inflammation caused by a combination of factors, whether chemical, perfusion of irritating medication; mechanical, due to the puncture site, type and fixation of the catheter and infectious, caused by the colonization of pathogenic agents whose origin is the skin and that migrate inward. Phlebitis involves an injury to the wall of the vein, and consequently, the patient will also be at risk of thrombus formation, which in turn leads to thrombophlebitis, deep vein thrombosis or pulmonary embolism. The existence of phlebitis involves intense and constant pain, with increased sensitivity and a sensation of heat and swelling. With the use of topical sesame oil, and thanks to its anti-inflammatory properties, the investigators intend to study whether it is effective in preventing the appearance of phlebitis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

300

Conditions

Phlebitis

Interventions

Sesame oilOTHER

A peripheral venous catheter will be channeled to the patient admitted to the unit and who requires it. The indications included in the guide for channeling venous access of the Marqués de Valdecilla hospital will be followed. Once the venous access has been channeled, it will be fixed with, leaving the puncture point visible for future monitoring. The sesame oil chosen for the project is "Sesame bio - 100% pure vegetable oil from the Naissance brand. To perform the procedure, two drops of sesame oil will be applied daily by the nurse in charge of the patient during the morning shift in the area about 2 cm above the insertion point and coinciding with the course of the vein channeled for intravenous therapy. A small massage of the area of application will be performed, with an approximate extension of 3x3cm, until its absorption. It will be left to dry in the air.

Saline solutionOTHER

After cannulation of the vein following the same procedure as explained in the intervention arm, patients belonging to the control arm will be administered two drops of saline solution.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Be over 18 years of age. * To be conscious and have a cognitive state that allows him/her to give consent to participate in the study. * Be diagnosed with a neoplasm that requires chemotherapy treatment. * To be a carrier of a CVP in the upper extremity as vascular access for chemotherapy administration. Exclusion Criteria: * Being allergic to sesame oil. * Be allergic to nuts. * Not being able to speak, read and write in Spanish. * Last days or palliative situation.

Outcomes

Primary Outcomes

Number of phlebitis in oncology patients with peripheral catheter to whom sesame oil is applied topically

Sesame oil will be applied in the intervention groups, with the aim of assessing whether its application decreases the occurrence of phlebitis in oncology patients with irritating and high osmolarity intravenous medication.

Time frame: one year

Secondary Outcomes

Other adverse effects that appear in relation to the topical application of sesame oil in patients with peripheral catheters

Registration of other adverse effects related to chemotherapy administration through a peripheral catheter: extravasation, number of cannulations during admission, catheter duration and reason for withdrawal.