Incidence, Clinical Characteristics and Outcomes of Unstable Angina in the contempoRary Area.

University Hospital, Montpellier210 enrolled

Overview

The study aims to evaluate clinical characteristics and prognostic of a contemporary population of patients with UA defined using T hs-cTn measurements The study includes all patients admitted in 2 French university centers with the confirmed diagnostic of UA defined with clinical ischemic symptoms and T hs-cTn concentrations \< 99 percentile (undetectable: \<5ng/l or non-elevated: \<14ng/l), or ≥ 99 percentile but mildly elevated (14-50ng/l) .The primary end-point included major events at 1-year follow-up (total mortality, new ACS, hospitalization for cardiac causes).

Study Type

OBSERVATIONAL

Enrollment

210

Conditions

Unstable Angina

Interventions

patients who underwent coronary angiographyPROCEDURE

All patients included in the ICAR project (Montpellier - Nîmes) benefit from a consultation at one year (12+or - 2 months), as they are systematically reviewed in our department: data will therefore be collected in the patient's medical record. Clinical biological parameters and events during the hospital phase are also collected in the patient's computerized record. Normal patient management remains unchanged.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion criteria: * Patients with ischemic symptoms at rest or minor exercise without evidence of acute myocardial necrosis. * Ischemic symptoms may include typical or atypical angina pectoris and worsening/deterioration of previously stable angina with or without electrical signs of ischemia on the electrocardiogram. * hs-cTn concentrations are in the normal range or may be slightly elevated \> 99th percentile (i.e. low troponin T elevation ≤ 50 \* Elecsys Roche) but with absence of significant kinetics according to criteria defined in the literature (\<20%). * One of the following angiographic criteria is required: * Coronary angiography revealing a stenosis with a diameter of at least 70%. * Stenosis of at least 50% diameter in the left common trunk. * FFR (Fractional Flow Reserve) documenting ischemia per coronary angiography of a coronary lesion in the case of intermediate stenosis (50-70%). * If there are no significant lesions, a spasm must be proven by an ergonovine test. Exclusion criteria: * NSTEMI and STEMI. * Coronaries normal or without significant lesions unless proven spasm.

Incidence, Clinical Characteristics and Outcomes of Unstable Angina in the contempoRary Area.

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes