Blastocystis and Cryptosporidium Infection in Colorectal Cancer Patients

N/ANot Yet RecruitingNCT06379035

Assiut University54 enrolled

Overview

1. Detect the prevelance of Blastocystis spp. and Cryptosporidium spp. among patients with colorectal cancer attending South Egypt Cancer Institute-Assiut University. 2. Detect the effect of Blastocystis and Cryptosporidium infection on various cytokines level in CRC patients that may be involved in the tumor progression.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Blastocystis Infection Cryptosporidium Infection Colorectal Cancer

Interventions

ELISA / PCRDIAGNOSTIC_TEST

Multiplex PCR for confirmation of diagnosis of Blastocystis and Cryptosporidium infection. Enzyme linked immunosorbent assay (Elisa) for detection of : Different cytokines level in Colorectal cancer patients that may be involved in the tumor progression due to Blastocystis and Cryptosporidium infection.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * The persons selected for the study are those who are: 1. Colorectal cancer confirmed patients by imaging techniques (CT or MRI) and histopathological biopsy by Colonoscopy. 2. Cooperative individuals attending South Egypt Cancer Institute - Assiut University of all ages and both sexes with confirmed diagnosis of CRC who agreed to be engaged in the study and were able to provide adequate samples. CRC Patients will be divided into 4 groups: Group 1: CRC patients without Blastocystis or Cryptosporidium infection. Group 2 : CRC patients with Blastocystis infection. Group 3 : CRC patients with Cryptosporidium infection. Group 4 : CRC patients with both Blastocystis and Cryptosporidium infection. Exclusion Criteria: * Patients having any type of tumors other than CRC. Patients taking anti-parasitic medications 2 weeks before sample collection.

Outcomes

Primary Outcomes

Detect the prevelance of Blastocystis spp. and Cryptosporidium spp. among patients with colorectal cancer attending South Egypt Cancer Institute-Assiut University.

Time frame: Baseline

Secondary Outcomes

Detect the effect of Blastocystis and Cryptosporidium infection on various cytokines level in CRC patients that may be involved in the tumor progression.

Time frame: Baseline

Central Contacts

Merna Hany, Master

CONTACT

01227994945 mirnahany14497@aun.edu.eg

Data from ClinicalTrials.gov

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