Access MeMed BV Assay Clinical Study Collection Protocol - Infectious Adult and Pediatric Cohorts

Inclusion Criteria: * Over 90 days of age. * Clinical suspicion of acute bacterial or viral infection. * Temperature ≥ 37.8°C (100°F) (any body site, any measurement device, including self-reported) or tactile fever, either of them noted at least once within the last 7 days. * Current disease duration ≤ 7 days. Exclusion Criteria: * Previously enrolled * Insufficient sample volumes obtained * For the adult and pediatric populations, \< 1.2 mL serum volume * Sample handling errors * Another unrelated episode of febrile infection within the past 2 weeks * Suspicion and/or confirmed diagnosis of infectious gastroenteritis/ colitis. * ≥48 hours of oral antibiotic treatment * ≥12 hours of intravenous\\intramuscular antibiotic treatment * Human Immunodeficiency Viruses (HIV), Hepatitis B Virus (HBV), or Hepatitis C Virus (HCV) infection (self-declared or known from medical records) * A proven or suspected infection on presentation with Mycobacterial (e.g., Tuberculosis, MAC), parasitic or fungal (e.g., Candida, Histoplasma, Aspergillus) pathogen * Active inflammatory disease (e.g., Inflammatory Bowel Disease \[IBD\], Systemic Lupus Erythematosus \[SLE\], Juvenile Idiopathic Arthritis \[JIA\], Rheumatoid Arthritis \[RA\], Kawasaki, other vasculitis) * Major trauma and\\or burns in the last 7 days. * Major surgery in the last 7 days * Congenital immune deficiency (CID) * Acquired immune deficiency\\modulation state including 1. Active malignancy treated within last 6 months 2. Current treatment with immune-suppressive or immune-modulating therapies, including without limitations: i. Administration of P.O.\\IV\\IM high dose steroids \>1mg/kg/day prednisone (or equivalent) at some point in the past 10 days or daily continuous use of steroids \> 0.25 mg/kg/day in the past 7 days ii. Monoclonal antibodies, anti-TNF agents iii. Intravenous immunoglobulin (IVIG) iv. Cyclosporine, Cyclophosphamide, Tacrolimus, Azathioprine, Methotrexate v. G/GM-CSF Interferons c. Post solid organ/bone marrow transplant patients d. Asplenia, sickle cell disease * Indwelling central venous catheter * Cystic Fibrosis * Pregnancy - self-reported or medically known * Other severe illnesses that affect life expectancy and quality of life such as: 1. Severe psychomotor retardation 2. Congenital metabolic disorder 3. End stage renal disease, advanced heart failure (NYHA 3/4), advanced COPD (GOLD 3/4)