The primary objective of this study is to validate controlled methods of wound, including 1%w/v SLS, 3%w/v SLS, and 24-24 times tape stripping, on the forearms of subjects. The study aims to standardize the procedures for creating wounds and systematically evaluate the effects of these methods on various skin parameters.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
5
This intervention is a moisturiging cream of concentration 5% for topical application to the respective test sites.
This intervention is a moisturiging cream of concentration 10% for topical application to the respective test sites.
This intervention is a 100% pure coconut oil product (Parachute Pure Coconut Oil) for topical application to the respective test sites.
NovoBliss Research Pvt Ltd
Gandhinagar, Gujarat, India
Trans Epidermal Water Loss (TEWL)
Using the Tewameter® TM Hex
Time frame: Days -02, -01, 01, 02, 05, 08, 28
Skin hydration
Using the Corneometer® CM 825
Time frame: Days -02, -01, 01, 02, 05, 08, 28
Skin surface topography
Assessment of skin smoothness, scaliness, roughness, wrinkles using the Visioscan® VC 20plus.
Time frame: Days -02, -01, 01, 02, 05, 08, 28
Dermatological Assessment
Visual dermatological evaluation of the skin using the Draize scale where 0 indicates no reactions and 4 indicates severe reactions
Time frame: Days -02, -01, 01, 02, 05, 08, 28
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