Resonance Breathing Training for Long Covid-related Myocardial Injury

Chengdu Sport University70 enrolled

Overview

An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Long COVID Myocardial Injury

Interventions

Resonance breathingOTHER

Resonant breathing was used on the subjects, using nasal inhalation and oral exhalation, for a total of 12 weeks.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age between 18 and 60 years; 2. According to the WHO definition: one or more systemic involvement present 3 months after the diagnosis of a new crown infection, and at least 2 of these months cannot be explained by other diseases 3. 2D-STE suggestive of GLSAVG: -17% ≤ men ≤ -10%, -18% ≤ women ≤ -10%; 4. Consent for enrollment based on the degree of myocardial injury, as diagnosed by a clinician; 5. Signing the informed consent form with the consent of the patient or his/her family members Exclusion Criteria: * (1) Previous history of coronary atherosclerotic heart disease and heart failure; (2) Combination of severe arrhythmia or cardiogenic shock; (3) Combination of severe hypertension, hypertrophic cardiomyopathy, valvular disease of moderate or higher grade, acute myocarditis or pericarditis; (4) Combination of any disease that severely affects limb movement, such as musculoskeletal system disease or severe hepatic or renal insufficiency; (5) Combination of progressive malignant tumors, infectious diseases, bleeding disorders, autoimmune diseases, etc; Those who have serious mental illness and are unable to cooperate

Outcomes

Primary Outcomes

New YorkHeart Association (NYHA)

The scale is divided into four levels Grade 1 is unrestricted activity. Daily physical activity does not cause significant shortness of breath, fatigue or palpitations Grade 2 is a mild limitation of activity. Asymptomatic at rest, daily activities may cause significant shortness of breath, fatigue or palpitations Grade 3 is marked limitation of activity. May be asymptomatic at rest, but may cause significant shortness of breath, fatigue, or palpitations with less than daily activity. Grade 4 is symptomatic at rest, with discomfort associated with any physical activity. Class IVa for those who can move around indoors or at the bedside without intravenous drug administration; Class IVb for those who cannot get out of bed and require intravenous drug administration.

Time frame: 12weeks

left ventricle global longitudinal strain, LVGLS

The magnitude of overall longitudinal myocardial strain in the left ventricle on two-dimensional speckle tracking echocardiograms as an average of the peak longitudinal strain in all myocardial segments. The normal range is (-25% to -17%) in men and (-25% to -18%) in women.

Time frame: 12weeks

Secondary Outcomes

hypertension

Blood pressure included both systolic and diastolic blood pressure and was observed before and after the intervention for any reduction in blood pressure.

Time frame: 12weeks

Average heart rate

One-minute average heart rate (at rest).

Time frame: 12weeks

Central Contacts

Rui Li

CONTACT

17711524016 wp100331@cdsu.edu.cn

Rui Li

CONTACT

17711524016

Data from ClinicalTrials.gov

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