Many patients undergoing inguinal hernia repair are prone to developing acute and chronic post-operative pain. The aim of the study is to show a possible correlation between pain and acute phase proteins in order to: * predict the severity of pain; * select most suitable pain relief therapy for the patient.
The day after surgery, some serum markers are determined by a blood sample. The markers analyzed are: * Leukocytes; * C-reactive protein (CRP); * D-dimer; * Fibrinogen; * Neutrophil-to-Lymphocyte Ratio (NLR). Pain level is assessed using the NRS scale at different times: * 1st post-operative day; * 7th post-operative day; * One month after surgery; * Three months after surgery; * Six months after surgery. Other data collected for the study are: gender, age, BMI.
Study Type
OBSERVATIONAL
Enrollment
71
A blood sample is taken the day after surgery
Augusto Lauro
Roma, Italy
RECRUITINGRelationship Between Post-operative Pain and C Reactive Protein (CRP) in Open Tension-free Inguinal Hernia Repair
The study compares post-operative pain, measured with the NRS scale, with CRP (μg/L) levels 24 hours after surgery
Time frame: one day
Relationship Between Post-operative Pain and D-dimer in Open Tension-free Inguinal Hernia Repair
The study compares post-operative pain, measured with the NRS scale, with D-dimer (μg/L FEU) levels 24 hours after surgery
Time frame: one day
Relationship Between Post-operative Pain and Fibrinogen in Open Tension-free Inguinal Hernia Repair
The study compares post-operative pain, measured with the NRS scale, with fibrinogen (g/L) levels 24 hours after surgery
Time frame: one day
Relationship Between Post-operative Pain and white blood cell count in Open Tension-free Inguinal Hernia Repair
The study compares post-operative pain, measured with the NRS scale, with white blood cell count (x 10\^9/L) 24 hours after surgery
Time frame: one day
Relationship Between Post-operative Pain and Neutrophil to Lymphocyte Ratio (NLR) in Open Tension-free Inguinal Hernia Repair
The study compares post-operative pain, measured with the NRS scale, with Neutrophil to Lymphocyte Ratio (NLR) 24 hours after surgery
Time frame: one day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.