The aim of the study is to investigate how the combination of ropivacaine (a slow onset, long duration local anesthetic) with lidocaine (a rapid onset, shorter duration local anesthetic) affects the onset and duration of a lateral infraclavicular plexus brachialis (LIC) block in patients undergoing non-acute hand surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
78
30 mL Ropivacaine 5 mg/mL (= 150 mg Ropivacaine)
20 mL Ropivacaine 5 mg/mL + 10 mL Lidocaine-Epinephrine (20 mg + 5 μg) / ml (= 100 mg Ropivacaine + 200 mg Lidocaine)
20 mL Ropivacaine 7,5 mg/mL + 10 mL Lidocaine-Epinephrine (20 mg + 5 μg)/mL (= 150 mg Ropivacaine + 200 mg Lidocaine)
Nordsjælland Hospital
Hillerød, Denmark
Total time to breakthrough pain
From the completion of the LIC block to first sensation of pain from the surgical area.
Time frame: 24 hours
The onset of sensory block
From the completion of the LIC block to complete sensory blockade * Tested with refrigerator-cold glass vials. * A 3-point scale is used for cold sensation assessment: 1 point = normal sensation of cold, 2 points = reduced sensation of cold and 3 points = no cold sensation. * A complete sensory blockade is defined as all four tested nerves obtaining three points on the 3-point scale (no cold sensation). This outcome is measured until the complete block is obtained, but no longer than 45 minutes. \- If a complete sensory block is not obtained after 45 minutes, the LIC block is viewed as a failed block.
Time frame: Until max 45 minutes
Total duration of sensory blockade
From the completion of the LIC block until the ending of sensory blockade
Time frame: 24 hours
Total duration of motor blockade
From the completion of the LIC block until the ending of motor blockade
Time frame: 24 hours
Degree of motor blockade
Measured according to Manual Muscle Testing scale (4 point scale) * At the time of complete sensory blockade (defined as all four tested nerves obtaining three points on the 3-point scale (no cold sensation)), or if complete sensory blockade is not obtained, the degree of motor blockade is tested at 45 minutes. * Assessment is done using a 4-point Manual Muscle Testing Scale: 3 points = no difference, movement against resistance is possible, 2 points = a slight difference, movement against slight resistance is possible, 1 point = significant difference, movement is significantly compromised, 0 point = paralysis.
Time frame: At complete sensory blockade and otherwise 45 minutes after block performance
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