To conduct a randomized crossover trial to determine the acute impact of exercise snacks on glycemic control in physically inactive individuals living with type 2 diabetes using continuous glucose monitoring.
Participants will perform two, 48-hour experimental conditions separated by 24 hours while wearing a continuous glucose monitor to measure glycemic responses. The order of the trials will be randomized for each participant. The two trials will include an exercise condition (EX) and a control, non-exercise condition (CON). During the EX trial, participants will perform four exercise snacks per day on two consecutive days (i.e., Monday and Tuesday). Each exercise snack will be 1-minute in duration and consist of bodyweight style exercise performed with vigorous effort. During the CON trial, participants will be asked to refrain from any structured exercise during two consecutive days (i.e., Thursday and Friday). All meals will be provided to participants during the two 48-hour trials and will be standardized for a given participant. There will be a one-day wash out period in between the completion of both trials for all participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Bodyweight-style exercise snacks lasting 1-minute each performed with vigorous effort 4 times per day on two consecutive days.
University of British Columbia Okanagan
Kelowna, British Columbia, Canada
RECRUITINGMean 24-h glucose concentration assessed using continuous glucose monitoring
The mean 24-h glucose per trial will be determined as the average of the two 24-h periods during that specific trial.
Time frame: 48-hour EX trial versus the 48-hour CON trial
Time in range determined using continuous glucose monitoring
Percentage of time in range (3.9-10 mmol/L)
Time frame: 48-hour EX trial versus the 48-hour CON trial
Time above range determined using continuous glucose monitoring
Percentage of time above range (\>10 mmol/L)
Time frame: 48-hour EX trial versus the 48-hour CON trial
Time below range determined using continuous glucose monitoring
Percentage of time above range (\<3.9 mmol/L)
Time frame: 48-hour EX trial versus the 48-hour CON trial
Glycemic variability determined using continuous glucose monitoring
Glycemic variability will be assess using the Standard Deviation (SD), mean amplitude of glycemic excursions (MAGE), and the coefficient of variation (CV)
Time frame: 48-hour EX trial versus the 48-hour CON trial
Two-hour glucose area under the curve following standardized breakfast, lunch and dinner meals
The incremental area under the curve following breakfast, lunch and dinner (2 h post meal)
Time frame: 48-hour EX trial versus the 48-hour CON trial
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