Factors Associated With Sub - Targeted Therapeutic Dose Of Renin - Angiotensin Blockage Among Chronic Heart Failure With Reduced Ejection Fraction Patients

Chulalongkorn University396 enrolled

Overview

Objective: To analyze factors associated with Thai heart failure with reduced ejection fraction patients who received sub-target doses of Angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor-neprilysin inhibitors (ARNIs), and angiotensin receptor blockers (ARBs). Methods: The retrospective cohort study was designed to collect data on Thai heart failure with reduced ejection fraction patients at Out-patient Clinic, Trat Hospital and Phrapokklao Hospital from January 2016 to December 2020. Thirteen factors were analyzed to determine their association with the sub-target group.

Study Type

OBSERVATIONAL

Enrollment

396

Conditions

Heart Failure With Reduced Ejection Fraction

Interventions

Renin-Angiotensin System InhibitorDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who were first diagnosed be heart failure with left ventricular ejection fraction less than 40%. * Received one of ACEIs,ARBs,ARNI drugs. Exclusion Criteria: * Electronic medical records was not complete enough to analyse. * Patients who had history of heart transplantation or had heart transplantation plan in last 12 months.

Outcomes

Primary Outcomes

factors associated with sub - target dose of ACEIs,ARBs,ARNI

factors associated with Thai heart failure with reduced ejection fraction patients who received sub-target doses of Angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor-neprilysin inhibitors (ARNIs), and angiotensin receptor blockers (ARBs).

Time frame: 12 months