Coconut Oil in Treatment of Periodontitis

Misr University for Science and Technology34 enrolled

Overview

Virgin Coconut Oil (VCO) is a vegetable oil extracted from coconut fleshcontains unsaturated fatty acids in the form of oleic acid and linoleic acid and flavonoids which function as anti-inflammatory. Periodontitis is an inflammatory disease of the periodontal tissues with a high prevalence worldwide. The main etiology of plaque periodontitis is biofilm containing colonies of pathogenic microorganisms. The aim of the study is to evaluate and compare the effect of scaling and root debridement alone versus the use of topically applied coconut oil as adjunctive to scaling and root debridement in treatment of Stage II and III Grade B periodontitis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Periodontal Diseases

Interventions

Eligibility

Sex: ALLMin age: 35 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients age group \>35 years without ant systemic disease * Willing to take part in the study. Patients with more than 16 natural teeth and have test teeth with both mesial and distal neighboring teeth with periodontitis with clinical attachment loss \>3 mm and radiographic percentage of bone loss/age ranged between 0.25 to 1. * Patients with no history of allergies to coconut Exclusion Criteria: * smokers * pregnant * lactating women * Teeth with both endodontic-periodontal lesion.

Outcomes

Primary Outcomes

clinical parameters

clinical attachment loss

Time frame: 3 months

clinical parameters

Probing depth

Time frame: 3 months

Secondary Outcomes

Biological parameters

Tumor necrosis factor alpha (TNF- α) levels by using ELISA.

Time frame: 3 months

Coconut Oil in Treatment of Periodontitis

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes