EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico

Fred Hutchinson Cancer Center

Overview

This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico. Smoking prevalence among sexual and gender minority (SGM) adults in New Mexico is more than twice as high as non-SGM adults. Helping young adult tobacco users to quit is critical, yet there have been few efforts to develop tailored treatments specifically for this population. EQQUAL-NM is a digital smoking cessation intervention designed specifically for SGM young adult smokers in New Mexico and may help them quit smoking.

OUTLINE: Participants are randomized to 1 of 2 groups. GROUP I: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program A) that helps explore personal values and teaches participants about smoking triggers and skills to help them manage cravings and accept thoughts and feelings related to smoking. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up. GROUP II: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program B) that is based on current clinical practice guidelines for tobacco cessation to help them quit smoking. This program helps with quit advice, tracking progress on quitting smoking, and managing cravings. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up. After completion of study intervention, patients are followed up at 3 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Conditions

Cigarette Smoking-Related Carcinoma

Interventions

Smartphone App-delivered Smoking Cessation InterventionBEHAVIORAL

Receive access to EQQUAL-NM (Program A) intervention

Smartphone App-delivered Smoking Cessation InterventionBEHAVIORAL

Receive access to EQQUAL-NM (Program B) intervention

Health Promotion and EducationOTHER

Receive text message reminders, motivational messages and prompts via SMS text messages (Program A)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Self-identify being between 18 and 30 years of age * Self-identify as a sexual and/or gender minority (i.e., a sexual orientation other than straight and/or gender that doesn't match sex assigned at birth) * Currently reside in New Mexico, with a New Mexico mailing address, and anticipate remaining in New Mexico for the duration of the study (3 months) * Self-report smoking at least 1 cigarette per week in the 30 days prior to screening * Own an Android phone or iPhone * Have at least weekly internet access for the next three months * Willing and able to stream audio and video for this study * Current use of a personal email account * Current use of text messaging * Interested in participating in the study for themselves (versus \[vs\] someone else) * Self-report that they have not participated in one of Fred Hutch's/NMSU's prior smoking cessation studies * Understand and agree to the conditions of compensation * Currently not incarcerated * Participants must be willing to use the assigned intervention program, complete the study assessments, and agree to the online consent form in English Exclusion Criteria: * Current use of other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed) * Member of the same household as another research participant * Previous use of the National Cancer Institute (NCI) QuitGuide app * Google voice number as sole phone number * Does not pass study fraud prevention protocol

Locations (1)

Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, United States

Outcomes

Primary Outcomes

Participant satisfaction

Self-report of satisfaction overall and with specific program components will be rated on a 5-point Likert-type scale. Higher scale scores indicate higher satisfaction with the app.

Time frame: At 3-month follow-up

Number of logins to the assigned application

Server-recorded number of app openings over 3 months

Time frame: Up to 3-month follow-up

Secondary Outcomes

Self-reported 7-day point prevalence abstinence (PPA) from all nicotine and tobacco products

Self-report of no nicotine/tobacco product use over the previous 7 days, with the exception of FDA-approved medications

Time frame: At 3 months

Biochemically confirmed 7-day point prevalence abstinence (PPA) from all nicotine/tobacco products

Self-report of no nicotine/tobacco product use over the previous 7 days, with the exception of FDA-approved medications, biochemically confirmed via saliva cotinine

Time frame: At 3 months

Self-reported 30-day PPA from all nicotine/tobacco products

Self-report of no nicotine/tobacco product use over the previous 30 days, with the exception of FDA-approved medications

Time frame: At 3 months

Biochemically confirmed 30-day PPA from all nicotine/tobacco products

Self-report of no nicotine/tobacco product use over the previous 30 days, with the exception of FDA-approved medications, biochemically confirmed via saliva cotinine

Time frame: At 3 months

Self-reported 7-day PPA from cigarette smoking

Data from ClinicalTrials.gov

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