Different Doses of Intravenous Administered Dexamethasone Effecting Brachial Plexus Supraclavicular Block

Hospital Universiti Sains Malaysia50 enrolled

Overview

To compare the analgesic properties of ultrasound guided supraclavicular block using ropivacaine 0.5% in arteriovenous fistula creation when used in combination with intravenous administered dexamethasone at 4mg and 8 mg as an adjuvant

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

End Stage Renal Failure

Interventions

supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous administered dexamethasoneDRUG

Comparing the onset of sensory, motor block, duration of motor block and analgesic duration

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: Adult, age 18 to 65 years End stage renal disease patients for AV fistula creation Exclusion Criteria: Not suitable candidate as determined by the primary team Refusal for brachial plexus block History of allergy to dexamethasone or local anesthesia Pregnancy History of previous brachial plexus injury Coagulopathy Local skin site infection Known neuropathy involving the arm undergoing surgery Patients with glucose reading more then 12mmol/

Outcomes

Primary Outcomes

To compare the difference of onset time between sensory and motor block of supraclavicular block between ropivacaine with IV dexamethasone 4mg and ropivacaine with IV dexamethasone 8mg

Time frame: 2 days

To compare the difference in duration of analgesia between supraclavicular block with ropivacaine and IV dexamethasone 4mg with ropivacaine and IV dexamethasone 8mg

Time frame: 2 days

Secondary Outcomes

To compare the duration difference of the return of motor block between supraclavicular block using ropivacaine with IV dexamethasone 4mg and ropivacaine with IV dexamethasone 8mg

Time frame: 2 days

Data from ClinicalTrials.gov

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