GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological pathologies by analyzing of coding and non-coding RNA contained in patients saliva. The study population consists of patients with clinically symptomatic females with one or more of the gynecological pathologies (endometriosis, adenomyosis, ovarian cysts, fibroids, ovarian/cervical/uterine cancer) and asymptomatic females. The patients concerned by the study will be managed without modification of the care pathway, nor modification of the therapeutic indications, nor modification of the diagnostic or follow-up examinations necessary according to the context, which are carried out according to the local recommendations.
Study Type
OBSERVATIONAL
Enrollment
2,500
Saliva sample
CHU d'Angers
Angers, France
NOT_YET_RECRUITINGClinique Tivoli Ducos - IFEMENDO
Bordeaux, France
RECRUITINGInstitut Bergonié
Bordeaux, France
NOT_YET_RECRUITINGCHU Caen
Caen, France
RECRUITINGCGFL
Dijon, France
NOT_YET_RECRUITINGCHU Lyon Sud
Lyon, France
NOT_YET_RECRUITINGAmerican Hospital of Paris
Neuilly-sur-Seine, France
NOT_YET_RECRUITINGCHU de Rennes Site Hôpital Sud
Rennes, France
NOT_YET_RECRUITINGClinique La sagesse
Rennes, France
NOT_YET_RECRUITINGCHU Rouen
Rouen, France
RECRUITING...and 3 more locations
Area under the curve (AUC) of the Receiver Operating Curve (ROC)
Identify a diagnostic signature for each pathology (Endometriosis / Adenomyosis / Ovarian cysts / Fibroids / Cervical Displasia / Ovarian cancer / Cervical cancer /Uterine cancer) by analyzing of coding and non-coding RNA contained in the saliva.
Time frame: Through the end of study inclusions, an average of 1 year
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