Testosterone abuse is extremely prevalent in athletes globally and especially in the United States professional sporting leagues
Because human bodies make testosterone naturally, it can be difficult to determine whether the testosterone in your body is natural or if it came from administering testosterone. Currently, testosterone abuse by athletes is detected by anti-doping laboratories in urine samples and use can also be inferred by testing blood samples. As a pharmaceutical preparation, testosterone is available to administer to your body in different ways. However, due to lack of controlled data on the various preparations of testosterone administrations related to the anti-doping field, this study id designed to look at five different testosterone preparations delivered three different ways and how they compare to each other in terms of anti-doping detection and how long they will be in circulation in your body.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
14
A single injection of testosterone
A daily dose of testosterone gel
A twice-daily pill of testosterone pill to swallow
Sports Medicine Research and Testing Laboratory
South Jordan, Utah, United States
Detection windows of testosterone administered via injection, oral and skin cream.
Changes in urinary testosterone/epitestosterone ratio after administration of testosterone in injection, oral and cream
Time frame: 12 weeks
Changes in serum concentration of testosterone
Changes in serum concentrations of testosterone in injection, oral and cream administration of testosterone
Time frame: 12 weeks
Changes in serum concentration of androstenedione
Changes in serum concentrations of androstenedione in injection, oral and cream administration of testosterone
Time frame: 12 weeks
Changes in serum concentration of luteinizing hormone
Changes in serum concentrations of luteinizing hormone after injection, oral and cream administration of testosterone
Time frame: 12 weeks
Direct detection of testosterone esters
Direct detection of testosterone esters
Time frame: 12 weeks
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