Visual Health Evaluation of Natural Color Display Technology

Beijing Tongren Hospital24 enrolled

Overview

Study on visual fatigue and visual function under changing ambient light color temperature by natural color mode: The influence of electronic display devices on visual fatigue of human eyes is the main evaluation index and the main outcome index of this experiment. Secondary outcome indicators were visual function indicators such as regulation and aggregation. There are other outcome measures: effective reading efficiency, blink detection, retinal fundus blood flow. The baseline values of the above indicators were respectively measured, and then the specific values of different indicators when the natural color mode was enabled and not enabled were collected under the changing ambient light color temperature, and the baseline values were statistically compared and analyzed. Evaluate the effect of natural color patterns on the relief of visual fatigue and on visual function.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Chromatic Adaptation

Interventions

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Adult population, regardless of gender 2. Refractive error is less than or equal to -2.5D and both eyes achieve corrected visual acuity of 0.8 or higher. 3. Normal intraocular pressure with no organic pathology. 4. No apparent symptoms of dry eye. 5. Willing to cooperate to complete all the tests. 6. Voluntarily signing the informed consent form. Exclusion Criteria: * 1: Individuals with strabismus and amblyopia exist. 2: Suffering from congenital eye conditions such as congenital cataracts or congenital retinal diseases. 3: Those who have undergone intraocular surgery (such as cataract removal, intraocular lens implantation, etc.). 4: Individuals with refractive media opacity (such as corneal lesions, lens opacity, etc.). 5: Abnormal intraocular pressure (IOP) (IOP \< 10 mmHg or IOP \> 21 mmHg, or a bilateral IOP difference of ≥5 mmHg). 6: Only one eye meets the inclusion criteria. 7: Active corneal infections such as bacterial, fungal, viral, or other acute or chronic anterior segment inflammations. 8: Currently using medications that may lead to dry eye or affect vision and corneal curvature. 9: Other ocular conditions, such as dacryocystitis, eyelid disorders and abnormalities, abnormal intraocular pressure, and glaucoma. 10: Unable to undergo regular eye examinations.

Outcomes

Primary Outcomes

Visual fatigue

The visual fatigue questionnaire utilized in this study consists of a self-report survey with a total of 19 items. It is designed to comprehensively assess the severity of visual fatigue symptoms, with a scoring system ranging from 1 to 7. Higher scores indicate more severe symptoms, encompassing three primary domains: ocular symptoms, visual discomfort, and psychological aspects triggered by visual fatigue.

Time frame: Each participant will complete the visual fatigue questionnaire, followed immediately by a VEP task, and then re-assess visual fatigue immediately afterward. This sequence will occur twice per group, totaling four assessments per participant.

Secondary Outcomes

Measurement of Accommodative Sensitivity with Flip-Chart Post-VEP Tasks

This clinical study involves the assessment of accommodative sensitivity for both monocular and binocular vision using a flip-chart immediately following each visual evoked potential (VEP) task. The measurement will quantify the number of optotypes correctly identified within one minute, indicative of the subject's accommodative capacity.

Time frame: Each participant will have three measurements: a baseline, and two post-VEP tasks, with immediate flip-chart tests after each task.

AC/A Ratio Measurement Post-VEP Tasks

This study involves the measurement of the AC/A ratio, which is a critical parameter in binocular vision assessment, reflecting the relationship between accommodation (focus adjustment) and convergence (ocular alignment). The AC/A ratio will be determined using the prism bar technique, which involve adding lenses to stimulate accommodation and measuring the resulting changes in convergence.

Time frame: Each participant will undergo three AC/A ratio measurements: at baseline and immediately after each of two VEP tasks.

Ocular Fundus Blood Flow

The study measured the sub foveal choroidal thickness, superficial vessel complex (SVC) density, and deep vessel complex (DVC) density, analyzing changes in retinal blood flow under the two modes.

Time frame: Retinal blood flow measurements should be taken within 3 minutes after the completion of each visual evoked potential (VEP) task. There are two VEP tasks per group, along with a baseline measurement, resulting in a total of three measurements.

Blink Frequency

Use electronic devices to record the number of clicks within 3 minutes and calculate the frequency.

Time frame: Blink frequency 3 minutes after the start of each visual evoked task and 3 minutes before the end

Reading efficiency

The number pairs were read in the first and last 10 minutes of the visual evoked task, and the number of number pairs read per minute was counted.

Time frame: The test was recorded 10 minutes after the start and 10 minutes before the end.