Compared to traditional blood glucose monitoring (TGM), CGM can accurately capture asymptomatic hyperglycemia and hypoglycemia events that are missed by TGM, accounting for 33% and 90% of cases, respectively. Real-time CGM provides instantaneous glucose levels and can also generate alarms for hypoglycemia and hyperglycemia based on preset glucose ranges, assisting patients in making timely adjustments to their glucose levels. Clinical studies have found that glucose control guided by real-time CGM is better, and the decrease in glycosylated hemoglobin levels is positively correlated with the frequency of CGM use. More importantly, although glucose variability can be calculated using conventional blood glucose measurements taken every four to six hours, to further assess precise changes in glucose levels, more detailed and accurate continuous data are required. In this respect, CGM has unparalleled advantages over traditional blood glucose monitoring.While the use of CGM in critically ill patients is still controversial.
We conducted this clinical study to compare the effectiveness of CGM and traditional blood glucose monitoring in guiding blood glucose control in critically ill patients, and to clarify the feasibility of using CGM for critically ill patients. We also aimed to explore the possible factors that affect CGM in critically ill patients.
Study Type
OBSERVATIONAL
Enrollment
360
Nanjing Drum Tower Hospital
Nanjing, Jiangsu, China
RECRUITINGCGM measurement
Test
Time frame: Days within the 1st week after ICU entrance
Whole blood or fingertip blood glucose measurement
Test
Time frame: Days within the 1st week after ICU entrance
ICU stay
Days
Time frame: During the ICU stay
28-day mortality rate
Mortality
Time frame: 28 days after ICU entrance
60-day mortality rate
Mortality
Time frame: 60 days after ICU entrance
Mortality rate during ICU stay
Mortality
Time frame: Days from ICU entrance to ICU discharge
Serum C-peptide
Test
Time frame: Days within the 1st week after ICU entrance
Insulin levels
Test
Time frame: Days within the 1st week after ICU entrance
Thyroid hormones and other relevant hormone levels were measured
Test
Time frame: The 1st day and the 7th day after ICU entrance
Wenkui Yu, Professor
CONTACT
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