This is a pilot study in healthy adult subjects to evaluate the safety and tolerability of AVT16 after administration of a single intravenous administration. Pharmacokinetics and immunogenicity of AVT16 will also be evaluated.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
18
Single intravenous administration of 300mg of AVT16
CCST
Christchurch, New Zealand
Incidence, nature and severity of Treatment Emergent Adverse Events
Safety and Tolerability of AVT16
Time frame: 18 weeks
Maximum Plasma Concentration (Cmax) of AVT16
Pharmacokinetic parameters
Time frame: 18 weeks
Frequency of anti-drug antibodies
Immunogenicity of AVT16
Time frame: 18 weeks
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