The aim of this observational register study is to establish a registry that completely records and compiles the data from routinely performed technical examinations (navigated transcranial magnetic stimulation, intraoperative neuromonitoring and stimulation, MRI imaging including tractography and connectome) and clinical tests over time (pre-, intra- and postoperative, under adjuvant therapy, as part of follow-up care) of patients with intracranial masses and lesions.
Study Type
OBSERVATIONAL
Enrollment
1,000
Department of Neurosurgery Heidelberg University Hospital
Heidelberg, Germany
RECRUITINGCognitive status
Higher cognitive functions - determined by the Montreal Cognitive Assessment (MocA)
Time frame: until last patient FU up to 48 months
Language status
Language function tested by the Aphasia Check List
Time frame: until last patient FU up to 48 months
Motor status
Motor function according to the BMRC scale
Time frame: until last patient FU up to 48 months
cortical data
cortical nTMS-Data - distribution according the cortical parellation system
Time frame: until last patient FU up to 48 months
Fiber tracts
Volume of fiber tracts
Time frame: until last patient FU up to 48 months
Fiber tracts
fractional anisotropy of fiber tracts
Time frame: until last patient FU up to 48 months
structural imaging (Connectome)
characteristics of Connectome and Disconnectome analysis (Global Efficiency value)
Time frame: until last patient FU up to 48 months
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