Otitis Media With Effusion and Type 2 Inflammation Diseases

Hearing and Language Healthcare Center, China Medical University Hsinchu Hospital, Taiwan100,622 enrolled

Overview

Otitis media with effusion (OME) is thought to be associated with comorbidities such as allergic rhinitis, gastroesophageal reflux disease, asthma, and more. Many of these comorbidities can be caused by type 2 inflammation (T2I). This study aims to characterize the risk of undergoing OME surgery. This retrospective, matched-cohort study involved the retrospective recruitment of patients from 2009 to 2020, using the Taiwan National Health Insurance Research Database (NHIRD)

Study Type

OBSERVATIONAL

Enrollment

100,622

Conditions

Otitis Media With Effusion

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of OME * At least two outpatient visits or one hospitalization record * Medical records within the database Exclusion Criteria: * Participants younger than 4 years old * Participants with unclear demographic information * Participants with a history of ear surgery or congenital ear anomalies * Participants who had undergone OME surgery before the index date

Outcomes

Primary Outcomes

The number of participants with OME who requiring surgical intervention

surgical intervention including procedures such as myringotomy and adenoidectomy

Time frame: 10 years

Data from ClinicalTrials.gov

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