Retrospective cohort study that evaluated 190 subjects admitted with diagnosis of hypertensive disorder of pregnancy, between 24 and 36 6/7 weeks, with an sFlt-1/PlGF index greater than or equal to 110. Data were collected on their clinical course prior to termination of pregnancy, using the last reported sFlt-1/PlGF ratio value to classify the population into four cohorts: values between 110-205, between 206 and 654, between 655 and 999 and greater than 1000.
Study Type
OBSERVATIONAL
Enrollment
190
No intervention. Clinical evolution was recorded, looking for perinatal complications.
Saint Thomas H
Panama City, Panama
Kidney injury
Creatinine level \> 1.1 Doubling of creatinine levels when others causes had been excluded
Time frame: From the moment of admission up until discharge after delivery, average 5 to 10 days
Hepatic enzyme abnormalities
Increase of liver enzyme to \> twice the upper limit of normal
Time frame: From the moment of admission up until discharge after delivery, average 5 to 10 days
HELLP Syndrome
Elevated liver enzymes Thrombocytopenia Hemolysis
Time frame: From the moment of admission up until discharge after delivery, average 5 to 10 days
Growth restricted fetus
Fetal weight below 10th percentile and abnormal doppler Fetal weight below 3th percentile
Time frame: From the moment of admission up until delivery, average 5 to 10 days
Stillbirth
Intrauterine fetal demise
Time frame: From the moment of admission up until discharge after delivery, average 5 to 10 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.