This study compares effects of plant based fiber vs fungi based fiber on clinical outcomes related to gut function (immunity, emotions, stress) and explores the role of gut microbiome structure and function on individual responses.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
8
fungal fiber from mycelium
long chain, degree of polymerization DP\>23
Consultorios Del Dr Jorge Eduardo Tartaglione
Buenos Aires, Buenos Aires F.D., Argentina
GastroIntestinal Quality of Life Index
GastroIntestinal Quality of Life Index (GIQLI), self assessed questionnaire, minimum score 0 (low quality), maximum score 144 (high quality)
Time frame: From enrollment to the end of treatment at 6 weeks
Bristol
Bristol scale and frequency chart. Frequency and consistence of feces, self assessed questionnaire. Range 1 to 7. Optimal value: 4. Values 1-3: different levels of constipation. Values 6-7: different levels of diarrhea
Time frame: From the enrollment to the end of treatment at 6 weeks
Wisconsin Upper Respiratory Symptom Survey
Wisconsin Upper Respiratory Symptom Survey (WURSS41) scale, self assessed questionnaire, range 0 (desired) to 301 (undesired)
Time frame: From enrollment to the end of treatment at 6 weeks
Positive and Negative Affect Schedule
PANAS, self assessed questionnaire. Range from 10 (lowest) to 50 (highest) for both positive and negative scale
Time frame: From enrollment to the end of treatment at 6 weeks
Work Productivity and Activity Impairment
WPAI, self assessed questionnaire, range 0 (desired) to 100 (undesired)
Time frame: From enrollment to the end of treatment at 6 weeks
basal cortisol
basal cortisol
Time frame: From enrollment to the end of treatment at 6 weeks
hs-CRP
high sensitivity C Reactive Protein
Time frame: From enrollment to the end of treatment at 6 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
calprotectin
fecal
Time frame: From enrollment to the end of treatment at 6 weeks
Short Chain Fatty Acids
fecal and serum SCFA
Time frame: From enrollment to the end of treatment at 6 weeks