Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation

China National Center for Cardiovascular Diseases464 enrolled

Overview

This study aimed to compare the efficacy of isolated coronary artery bypass grafting and coronary artery bypass grafting + mitral valve repair in moderate ischemic mitral regurgitation patients through a cohort and explore the potential risk factors of the clinical outcomes.

Study Type

OBSERVATIONAL

Enrollment

464

Conditions

Mitral Valve Insufficiency Mitral Valve Annuloplasty Coronary Artery Bypass

Interventions

mitral valve repairPROCEDURE

coronary artery bypass grafting concomitant mitral valve repair

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Adult coronary artery disease patients complicated with moderate ischemic mitral regurgitation. 2. undergoing coronary artery bypass grafting with or without mitral valve repair. Exclusion Criteria: 1. patients under the age of 18 years, 2. patients complicated with more than moderate ischemic mitral regurgitation or undergoing mitral valve replacement, 3. patients complicated with primary mitral valve disease other than ischemic mitral regurgitation, such as rheumatic mitral regurgitation or mitral valve leaflet prolapse, 4. patients undergoing concomitant aortic valve procedure.

Locations (1)

Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, China

Outcomes

Primary Outcomes

major adverse cardiovascular and cerebrovascular events

the composite of all-cause death, rehospitalization for heart failure, non-fatal myocardial infarction, non-fatal stroke or repeat mitral valve surgery.

Time frame: 2years

Data from ClinicalTrials.gov

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