Protein supplementation is one of the main recommendations for regular endurance physical exercise (RT). In older people, the need for protein increases particularly in the face of physiological and pathophysiological changes associated with the loss of muscle tissue and function, so protein intake becomes more relevant in this population. Fermented dairy products such as yogurt, and especially those with an extra protein content, have increased their popularity and consumption in the national market. Their nutritional composition is of particular interest, given their amino acid profile and in particular their high Leucine content, which could be compared with the classic protein supplements recommended for muscle gain and recovery. Objective: To analyze the effect on body composition, lipid profile, physical condition and muscle functionality induced by the intake of high protein yogurts versus Whey protein together with a muscular resistance program in elderly people. Hypothesis: The intake of high protein yogurts will lead to equal or greater gains in muscle mass, physical condition and functionality than those obtained with the intake of Whey protein together with resistance training in elderly people.Methodology: 16 healthy, lactose intolerant free, older (60-75 years old) subjects will be recruited to perform 8 weeks of muscular resistance training (RT) 3 times per week, who will be randomly supplemented with high protein yogurt (PY) or Whey protein (WP). At baseline and at the end of the intervention, body composition will be assessed by DEXA, muscle strength, maximal oxygen consumption and lipid profile. Expected Results: The YPRT group is expected to achieve similar or greater increases in muscle strength, fat-free mass, lipid profile and decrease in fat mass than the WP group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
18
WP group received 25g protein on one scoop of Whey Protein Isolate (Iso100 Dymatize) with 8 weeks of resistance training 3 days a week.
PY group received 24.6g protein on two High Protein yogurts (Lonco Leche) with 8 weeks of resistance training 3 days a week.
Motion Health and Performance Center
Santiago, Chile
Body Composition
Changes in weight, total fat mass, total skeletal muscle mass, segmental fat and muscle mass
Time frame: From Baseline, up to 56 days
Blood Lipids
Changes on Serum Triglycerides, Total Cholesterol, and High Density Cholesterol (mmol/L)
Time frame: From Baseline, up to 56 days
Muscle Strength
Determine by Isometric mid-tight pull (Newton, N)
Time frame: From Baseline, up to 56 days
Handgrip
Handgrip Strength measured on left and right hand (kg)
Time frame: From Baseline, up to 56 days
Time Up and Go
Length of time from sitting-walk-sit (seconds)
Time frame: From Baseline, up to 56 days
Isokinetic Muscle Strength
Maximal peak torque from left and right quadriceps and hamstrings (N/m)
Time frame: From Baseline, up to 56 days
Aerobic Capacity
Maximal Oxygen Consumption determine by the volume of oxygen (L/min)obtained on a incremental test
Time frame: From Baseline, up to 56 days
Resting Metabolic Rate
Determine by indirect calorimetry (kcal/d)
Time frame: From Baseline, up to 56 days
Evaluation of the intestinal microbiota
Fecal microbiota analysis based on the 16S ribosomal RNA (rRNA) sequencing pre- and post-dietary intervention.
Time frame: From Baseline, up to 56 days
Food Consumption
24h food recall
Time frame: From Baseline, up to 56 days
Evaluation of liver characteristics profile
Uric acid, BUN, Albumin, Creatinine aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), gamma-glutamyltransferase (GGT) after every intervention and wash-out in plasma (mmol/L).
Time frame: From Baseline, up to 56 days
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