This study aims to confirm the positive effect of the Red Panax Ginseng on the cognitive performance and regulation of stress and fatigue in adults with moderate stress level.
This study has been designed as a randomized double-blind placebo-controlled interventional study. One hundred and fifty participants (aged between 18 and 60), presenting a moderate level of perceived stress, were randomly allocated to the control (placebo) or test (ginseng supplement) group. Participants will be supplemented during 3 weeks with those products. Cognitive performance and emotional processing will be measured with tests and questionnaires before (baseline) and at the end (3 weeks) of the intervention. Fasted blood glucose level will be measured in blood before (baseline) and at the end (3 weeks) of the intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Enrollment
150
One tablet per day for 3 weeks consumed for subjects randomized in the Dietary supplementation group. This will lead to an intake of 200mg per day of Red Panax Ginseng (corresponding to 22.4mg of ginsenosides and 20.2mg of rare ginsenosides).
One tablet per day consumed for 3 weeks for subjects randomized in the Control group. The product is composed of rice flour (50mg) and brown sugar (150mg).
Center of Investigation in Clinical Nutrition (CICN)
Louvain-la-Neuve, Belgium
A decrease of stress level
Comparison between groups of the adjusted for baseline stress level assessed by the Perceived Stress Scale (PSS)
Time frame: 3 weeks
Evolution of depression state
Comparison between groups of the adjusted for baseline of depression state (BDI)
Time frame: 3 weeks
Evolution of anxiety state
Comparison between groups of the adjusted for baseline of anxiety state (STAI-S)
Time frame: 3 weeks
Evolution of emotional processing
Comparison between groups of the adjusted for baseline of emotional processing assessed by the PANAS
Time frame: 3 weeks
Evolution of fatigue level
Comparison between groups of the adjusted for baseline of fatigue level (PIC)
Time frame: 3 weeks
Evolution of attentional performance
Comparison between groups of the adjusted for baseline of attentional performance assessed by the Reaction Time and Rapid Visual Information Processing subtests of CANTAB.
Time frame: 3 weeks
Evolution of memory performance
Comparison between groups of the adjusted for baseline of memory performance assessed by the Verbal Recognition Memory, Paired Associate Learning and Spatial Span subtests of CANTAB.
Time frame: 3 weeks
Evolution of executive functions performance
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Comparison between groups of the adjusted for baseline of executive functions performance assessed by the Multitasking Test and One Touch Stockings of Cambridge subtests of CANTAB.
Time frame: 3 weeks
The intervention satisfaction of the volunteer
Comparison between groups of the adjusted for baseline of the intervention satisfaction of the volunteer, evaluated by a Likert scale
Time frame: 3 weeks