This study aims to determine the prognosis of heart failure in our population by using multiple validated risk scores and to evaluate the strengths of these scores in assessing prognosis with better discrimination.
After fulfilling the eligibility criteria, informed consent will be obtained from all the patients regarding using data for research while maintaining anonymity. All the included patients will be interviewed by the assigned physician to complete the detailed questionnaire, including patient demographics, risk factors, and validated questionnaires including the Acute Decompensated Heart Failure National Registry (ADHERE), The Get With The Guideline-Heart Failure (GWTG-HF) Risk Score, the Ottawa Heart Failure Risk Scale (OHFRS), and EHMRG30-ST score. All the patients will be followed after 30 days, and survival status will be obtained. The AUC of the GWTG-HF risk score for all-cause death was 0.687 (95% CI, 0.649-0.725) \[18\], at 95% confidence interval, ±3% margin of error, the sample size was calculated to be n=626 patients. The calculated sample size was inflated by a factor of 1.5 for the design effect; hence, the sample size for the study will be N=939. For data verification, 10% of the data will be cross-checked with the source document (Patient file).
Study Type
OBSERVATIONAL
Enrollment
1,000
Consecutive patients presented at Emergency Departement with Acute Heart Failure
National Institute of Cardiovascular Diseases
Karachi, Sindh, Pakistan
RECRUITINGIn-Hospital Prognosis
Factors affecting in-hospital prognosis of patients with acute heart failure presented at Emergency of a tertiary care hospital
Time frame: From admission till discharge/death
30-day Prognosis
Factors affecting the 30-day prognosis of patients with acute heart failure either via telephonic contact or re-admission or via OPD.
Time frame: From day of admission of last visit till 30 days
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