A Study to Evaluate the Impact of Clascoterone 1% Cream on Skin Barrier Properties in Acne Prone Patients

Inclusion Criteria: 1. Subjects who self identify as having sensitive acne prone skin. 2. Female or male subjects 18+ years of age. 3. Subjects with Fitzpatrick skin types I-VI. 4. Subject agrees not to introduce any new colored cosmetics (lipsticks, eye shadows, facial foundations, blush, powder) or skin care products during the study. 5. Subjects must be willing to use only a cleanser and sunscreen on the entire face and no other skin care products. 6. Subjects must be willing to use the Winlevi study product to designated half face. No other topical acne treatment products on the entire face for the 2 week duration of the study. 7. Subject has signed an Informed Consent Form in compliance with 21CFR Part 50: "Protection of Human Subjects." 8. Subject is dependable and able to follow directions and is willing to comply with the schedule of visits. 9. Subject is in generally good physical and mental health. Exclusion Criteria: 1. Any dermatological disorder, which in the investigator's opinion, may interfere with the accurate evaluation of the subject's skin characteristics, except for the conditions associated with sensitive skin. 2. Subjects who are not willing to use only the assigned study product and nothing else one randomized half face, except for cleanser and sunscreen that must remain unchanged during the study. Moisturizers or topical acne treatment products should not be used during the 2 week study period on either side of the face. 3. Subjects who do not agree to refrain from direct sun exposure during the study duration. 4. Subjects who have demonstrated a previous hypersensitivity reaction to any of the ingredients of the study products. 5. Subjects, who are pregnant, breast feeding, or planning a pregnancy. 6. Subjects with clinically significant unstable medical disorders. 7. Subjects who are unwilling or unable to comply with the requirements of the protocol. 8. Subjects who have history of a psychological illness or condition that would interfere with their ability to understand and follow the requirements of the study. 9. Subjects who are currently participating in any other clinical study. 10. Subjects with any planned surgeries and/or invasive medical procedures during the course of the study. 11. Subjects who currently or frequently use high doses of anti-inflammatory drugs for a defined medication condition. Aspirin use should not exceed 2 tablets (650 mg) per day. 12. Subjects currently receiving any anticancer, immunosuppressive treatments/ medications (e.g., azathioprine, belimumab, cyclophosphamide, Enbrel, Imuran, Humira, mycophenolate mofetil, methotrexate, prednisone, Remicade, Stelara.), or radiation as determined by the initial paperwork. 13. Subjects with a history of immunosuppression/immune deficiency disorders (including (HIV infection or AIDS) or currently using immunosuppressive medications (e.g., azathioprine, belimumab, cyclophosphamide, Enbrel, Imuran, Humira, mycophenolate mofetil, methotrexate, prednisone, Remicade, Stelara) and/or radiation as determined by study documentation.