This proof-of-concept study will evaluate the impact of surgically placing and stimulating the hypoglossal nerve and/or a second neural target Ansa Cervicalis, with a set of off-the-shelf electrode arrays.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
7
Device stimulation of the hypoglossal nerve and/or Ansa Cervicalis
University College London Hospital
London, United Kingdom
Incidence of participants with changes in cross-sectional area airway opening during target stimulation
Assessment of patients with changes in acute cross-sectional area airway opening measured in cm2 under nasoendoscopy when stimulating two neural targets (the HGN and AC). Video imaging and physician interpretation of nasoendoscopic images will be used to review outcome measures.
Time frame: Day 0
Assessment of changes in airflow outcomes
Assessment of acute changes in airflow when stimulating the HGN in combination with the AC during a flow limited event (hypopnea or apnea).
Time frame: Day 0
Number of participant adverse events observed during the study
To evaluate and report all observed participant adverse events observed during study.
Time frame: Day 30
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