The aim of this project is to further examine the effectiveness of Rhythmic Sensory Stimulation (RSS) with low-frequency sounds and somatosensory stimulation as a complementary therapy for fibromyalgia, and to investigate potential mechanisms underlying the effects of RSS on chronic pain.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Participants will undertake 15 self-administered sessions of RSS 40Hz low frequency sound stimulation, 30 minutes daily, over 3 weeks (5 days/week).
change in inflammatory cytokine levels
The investigator will use a multiplex enzyme-linked immunosorbent assay (ELISA) to asses inflammatory cytokines in fibromyalgia.
Time frame: baseline, 1 month, 2 months
change in pain severity
Patients will rate their pain severity on a scale from 0 (no pain) to 10 (extreme pain)
Time frame: baseline, 1 month, 2 months
change in EEG brain activity
The investigators will measure EEG dynamics to quantify dysfunctional activity in brain areas that are affected by fibromyalgia
Time frame: baseline, 1 month, 2 months
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