Vienna Hypothermic Oxygenated Machine Perfusion Study

Medical University of Vienna500 enrolled

Overview

In this observational cohort study data on all patients undergoing liver transplantation after hypothermic oxygenated machine perfusion at Medical University of Vienna will be prospectively recorded. Investigation of short- and long-term outcome in this cohort will be conducted.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

End Stage Liver Disease Hepatocellular Carcinoma

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients undergoing liver transplantation with the use of hypothermic oxygenated machine perfusion * age ≥ 18 years Exclusion Criteria: * pregnancy * partial grafts * the anatomical integrity of the liver is not preserved in a way that makes the perfusion of the liver possible

Locations (1)

Medical University of Vienna

Vienna, Austria

RECRUITING

Outcomes

Primary Outcomes

Incidence of ischemic-type biliary lesions

Non-anastomotic stenosis, post-transplant cholangiopathy

Time frame: Within one year after liver transplantation

Secondary Outcomes

Rate of early allograft dysfunction

Deviation of bilirubin, transaminases or international normalised ratio

Time frame: Evaluated within the first 7 postoperative days

Rate of primary non-function

Time frame: Evaluated in the immediate postoperative period, specifically within the first postoperative week

Incidence of re-transplantation

Time frame: Evaluated in the immediate postoperative period, specifically within the first postoperative week

Central Contacts

David Pereyra, MD, PhD

CONTACT

+4314040056210 david.pereyra@muv.ac.at

Jule Dingfelder, MD

CONTACT

+4314040056210 jule.dingfelder@muv.ac.at

Data from ClinicalTrials.gov

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