Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms

Inclusion Criteria: 1. Ambulatory, male or female, 21-70 years of age 2. A BMI of 18.5 -34.9 3. . Experiences at least three conditions involving gastrointestinal health on a weekly basis 4. Are comfortable fasting overnight 5. Are able to complete study procedures for up to approximately 6 hours on 2 separate days 6. Considered to be generally healthy on the basis of medical history 7. Willing to follow study instructions, including compliance with the study procedures and requirements Exclusion Criteria: 1. Unable to provide a urine specimen, stool specimen or blood sample from a finger stick 2. Currently on a galactose/lactose restricted diet 3. Having taken proton pump inhibitors within the past 3 months 4. History of oral antibiotic use within the past 3 months 5. Current or previous history of gastrointestinal disease, cancer, infection or surgery that may interfere with the outcome parameters 6. A medical or surgical event requiring hospitalization, outpatient visits or emergency room visits within the past 5 years or in the judgment of the Study Investigator /Sub-I would preclude participation in the study 7. Current or previous history of diabetes 8. History of a major change in dietary habits with the past 1 month 9. Known intolerance or allergy to sugar alcohols including mannitol, sorbitol, xylitol, lactulose or lactose 10. Women who are lactating, pregnant or planning pregnancy within the next two months 11. Having donated blood or received a blood transfusion within 30 days before screening 12. Currently participating in another clinical research study or participated in another clinical research study within 30 days prior to screening