An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence

N/ARecruitingNCT06420219

University of Southern California50 enrolled

Overview

This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.

PRIMARY OBJECTIVE: I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes. OUTLINE: This is an observational study. Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Head and Neck Carcinoma

Interventions

Non-Interventional StudyOTHER

Non-interventional study

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis/disease status: New diagnosis of head and neck cancer * Allowable type and amount of prior therapy: No prior treatment * Age ≥ 18 years. * Ability to understand and the willingness to sign a written informed consent. Exclusion Criteria: * Patients who have had treatment of head and neck cancer

Locations (1)

USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States

RECRUITING

Outcomes

Primary Outcomes

Overall survival

Time frame: Up to 5 years

Disease free survival

Time frame: Up to 5 years

Central Contacts

Sandy Tran, MS

CONTACT

323-865-0451 sandy.tran@med.usc.edu

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.