This is a parallel and randomized-controlled clinical study aimed to identify the optimized size of atomized particles of 2% lidocaine that can provide the best topical anesthesia during ATI. To determine the effect of nebulization with different sizes of atomized particles of 2% lidocaine on cough, reaction, and comfort during ATI in patients with predicted difficult airway.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Enrollment
230
Participants received 2% lidocaine by atomizer.
Henan Provincial People's Hospital
Zhengzhou, Henan, China
cough score
Investigators will record cough score during intubation.
Time frame: during intubation
reaction and discomfort scores
Investigators will record reaction and discomfort scores during intubation.
Time frame: during intubation.
intraoperative hemodynamic parameters
endotracheal tube insertion inflation of the tracheal tube cuff systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR)
Time frame: endotracheal tube insertion, inflation of the tracheal tube cuff and 1 minute after endotracheal tube insertion
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