PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7

Inclusion Criteria: * Patients who have been diagnosed with advanced hepatocarcinoma (HCC), confirmed histologically or clinically. * Patients with Barcelona (BCLC) stage B and C beyond up to seven; * Have not received any prior systemic therapy for HCC (including: chemotherapy, molecular targeted therapy, immunotherapy); * Receiving only post-marketing PD-1/PD-L1 inhibitors in combination with anti-angiogenic agents (including, but not limited to, drugs containing hepatocellular carcinoma indications); \*The interval between the first use of PD-1/PD-L 1 inhibitors and the use of anti-angiogenic drugs is ≤ 1 week * TACE was performed within 1 month prior/after the first PD-1/PD-L 1 inhibitor/antiangiogenic drug treatment; * TACE treatment followed by at least 1 cycle of combination therapy, including: cTACE and DEB-TACE; * There is at least 1 measurable lesion in the liver according to RECIST v1.1 criteria Exclusion Criteria: * Cholangiocellular carcinoma, mixed hepatocellular carcinoma, sarcomatoid hepatocellular carcinoma, or hepatic fibrous laminar carcinoma that has been pathologically/histologically confirmed; * Patients who do not meet the above definition of combination therapy; * Patients had malignant tumors other than HCC within 5 years prior to enrollment (except cured limited tumors, including cervical carcinoma in situ, basal cell carcinoma of the skin, and prostate carcinoma in situ)