The aim of this study is to clinically evaluate the efficacy of Insulin like Growth Factor (IGF-1) on bone regeneration in intrabony defects.
In test group, after reflection of flap and degranulation, IGF-1 gel with hydroxyapatite will be placed in the defect and sutures will be placed. In control group, after reflection of flap and degranulation, hydroxyapatite will be placed in the defect and sutures will be placed.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
After degranulation of the defect, IGF-1 gel mixed with Hydroxyapatite graft will be placed in the defect.
After degranulation of the defect, Hydroxyapatite graft will be placed in the defect.
SVS Institute of Dental Sciences, Mahabubnagar
Hyderabad, Telangana, India
RECRUITINGBone Regeneration
Radiovisiography (RVG) will be used to assess bone regeneration achieved post operatively after 3 months and 6 months.
Time frame: 3 months and 6 months
clinical attachment level
Assessment of clinical attachment level using UNC-15 probe at baseline and post operatively at 3 and 6 months.
Time frame: 3 months and 6 months
Probig depth
Assessment of probing depth using UNC-15 probe at baseline and postoperatively at 3 and 6 months.
Time frame: 3 months and 6 months
Plaque Index
Assessment of plaque (PI) - according to Turesky modification of Quigley and Hein Plaque Index, 1970.
Time frame: 3 months and 6 months
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