The primary aim of this clinical trial is to determine the acute effects of OLIPOP (a lower sugar, high fiber prebiotic soda) consumption, compared to consumption of a commercially available sugar-sweetened soda pop, on blood glucose in response to the beverages alone and in combination with a carbohydrate-rich mixed lunch meal in free-living, generally healthy adults.This study will consist of one screening/randomization clinic visit (day 0) and one follow-up clinic visit (day 5), with participants consuming study products on their own (e.g., at home) following an assigned treatment sequence on days 1, 2, 3, and 4. The main questions answered by this trial are the impacts of a prebiotic rich soda versus a traditional soda on: 1) blood glucose levels with and without a meal, 2) perceived hunger levels, 3) perceived alertness levels and 4) total caloric intake.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
30
12oz serving containing Carbonated Water, OLISMART(TM) (Cassava Root Fiber, Acacia Fiber, Guar Fiber, Nopal Cactus\*, Marshmallow Root\*, Calendula Flower\*, Kudzu Root\*), Cassava Root Syrup, Apple Juice Concentrate, Lime Juice, Natural Cola Flavor, Alpinia Galanga Root\*, Stevia Leaf\*, Himalayan Pink Salt, Green Tea Caffeine\*, Natural Caramel Flavor, Natural Vanilla Flavor, Cinnamon\* (\*Extract)
12oz serving containing carbonated water, high fructose corn syrup, caramel color, phosphoric acid, natural flavors, caffeine
Biofortis
Addison, Illinois, United States
Blood Glucose iAUC
Incremental area under the curve (iAUC) for glucose from t = -30 min prior to test product consumption to t = 120 min following test-product consumption (iAUC0-120 min), where t = 0 is the start of beverage consumption either alone or in combination with a meal (depending on the test sequence).
Time frame: For 2 hours post intervention
Blood Glucose Cmax
Blood glucose maximum concentration
Time frame: For 2 hours post intervention
Time to Blood Glucose Cmax (Tmax)
Time to maximum blood glucose concentration
Time frame: For 2 hours post intervention
Blood Glucose Rise 0-2 Hours
The maximum concentration above the average baseline glucose concentration within the 2-hour period following study product consumption, expressed as a percentage of the average baseline glucose concentration
Time frame: For 2 hours post intervention
Blood Glucose Dip 2-3 Hours
The difference between the lowest glucose concentration in hours 2-3 after study product consumption and the average baseline glucose concentration, expressed as a percentage of average baseline glucose concentration
Time frame: For time frame of 2 to 3 hours post intervention
Blood Glucose Reduction
The number of participants with a reduction in glucose in hours 2-3 after study product consumption compared to the average baseline glucose concentration
Time frame: For time frame of 2 to 3 hours post intervention
Time Until Next Meal
The number of minutes after consumption of the study product that elapsed before the next meal of at least 50 kcal is consumed
Time frame: Within same day post interevention
Energy Intake - Short Term
Energy intake (kcals) within 3 to 4 hours post-product consumption
Time frame: For time frame of 3 to 4 hours post intervention
Energy Intake - 24 Hours
The total daily consumption covers the full period from 4 hours before the participant's breakfast to 20 hours after
Time frame: Time frame from 4 hours before the participant's breakfast to 20 hours after participant's breakfast
Change in Perceived Hunger Level
The change in hunger ratings from pre-meal to post meal where post meal is defined as the average of the hunger ratings in the 2- 3 hour time frame
Time frame: For time frame of 2 to 3 hours post intervention
Change in Perceived Alertness Level
The change in alertness ratings from pre-meal to post meal where the post meal is defined as the average alertness ratings in the 2-3 hour time frame
Time frame: For time frame of 2 to 3 hours post intervention
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