Multi-site randomized trial of the THRIVE digital health application versus usual care to evaluate the effect of THRIVE on quality of life (QOL), physical and psychological symptoms, coping, and self-efficacy in 250 patients with newly diagnosed advanced lung cancer.
Multi-site randomized controlled trial of the THRIVE digital health application versus usual care in 250 patients diagnosed with advanced lung cancer within the previous 12 weeks to examine the effect of the intervention on patient-reported QOL, physical symptoms, anxiety and depression symptoms, coping, and self-efficacy. Participants will be randomized in a 1:1 fashion and stratified by study site and lung cancer type to ensure a balanced representation of these factors between the two study groups. The study team will provide iPads to patients assigned to THRIVE and provide instructions on how to use the iPad and digital app. The study team will administer patient-reported outcome measures at enrollment and again at six, 12, and 24 weeks post-enrollment to evaluate the short and long-term impact of THRIVE.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
250
access to a digital health app
University of California Los Angeles
Los Angeles, California, United States
RECRUITINGVeteran Affairs Greater Los Angeles Health Care
Los Angeles, California, United States
NOT_YET_RECRUITINGMassachusetts General Hospital
Boston, Massachusetts, United States
RECRUITINGFunctional Assessment of Cancer Therapy - Lung (FACT-L)
Quality of Life (higher scores indicate better quality of life)
Time frame: 12 weeks
MD Anderson Symptom Inventory (MDASI)
Physical Symptoms (higher scores indicate worse symptoms)
Time frame: 12 weeks
Hospital Anxiety and Depression Scale (HADS)
Anxiety and Depression Symptoms (higher scores indicate worse symptoms)
Time frame: 12 weeks
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